Figure 7. Ghrelin degradation is reduced in vitro by human IgG.

Ghrelin concentrations after incubation of ghrelin (30 fmol ml⁻¹) in the IgG-deprived plasma effluents for 2 h at 37°C with and without human IgG (a). Estimation of ghrelin protection efficiency from degradation by the ratios of ghrelin concentrations measured after incubations of ghrelin with IgG versus ghrelin alone (b). (a) M–W tests ***P<0.001, Student’s t-tests ^#P<0.05 versus controls; (b) Student’s t-tests *P<0.05. (n=6, error bars, s.e.m.).