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ABCA1-mediated cholesterol efflux from J774 mouse macrophages treated with cpt-cAMP using WT apoA-I and the apoA-I[225–230] mutant as cholesterol acceptors (A). LCAT activation capacity of WT apoA-I and the apoA-I[225–230] mutant. Experiments were performed as described in Materials and Methods. The data represent the average from two independent experiments performed in triplicate (B).
