Fig. 1.
Comparison of partial sequences of DOX and CYP domains. A: Partial alignment of the DOX domains of COX-1 and -2, 7,8- and 5,8-LDS, ATEG_02036, and FOXB_01332 by ClustalW. The catalytically important Tyr residue and the proximal His ligand are in red, and differences to COX within the tetramer are marked blue. B: Partial alignment of CYP domains of 7,8- and 5,8-LDS by ClustalW. C: Partial alignment of ATEG_02036 and FOXB_01332 by ClustalW. The conserved motifs of aspergilli with catalytically important Asn and Gln residues are marked red along with the aligned residues of FOXB_01332 marked blue. 7,8-LDSgg, 7,8-LDS from Gaeumannomyces graminis; 5,8-LDSat, 5,8-LDS from A. terreus.