Table S2.
MBC of antibiotics (μg/mL) against pathogenic microorganisms in the presence and absence of AgNPs
| Antibiotics |
Escherichia coli ATCC 25922 |
Acinetobacter baumannii AIIMS 7 |
Enterobacter aerogenes NCIM 2964 |
Pseudomonas aeruginosa NCIM 5029 |
Shigella sonnie MTCC 2957 |
Salmonella typhimurium NCIM 2501 |
Staphylococcus aureus MTCC 3160 |
Streptococcus mutans MTCC 497 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | |
| Aminoglycosides | ||||||||||||||||
| Amikacin | 1 | <0.015 | 128 | 2 | 1 | <0.015 | 0.5 | <0.015 | 0.5 | <0.015 | 1 | <0.015 | 1 | <0.015 | – | – |
| Gentamicin | 0.25 | <0.015 | 512 | 2 | 0.25 | <0.015 | 0.125 | <0.015 | 0.06 | <0.015 | 0.5 | <0.015 | 0.125 | 0.125 | – | – |
| Kanamycin | 1 | 0.125 | – | – | 256 | 0.125 | 512 | 2 | 0.5 | <0.015 | 2 | <0.015 | 1 | 0.125 | – | – |
| β-Iactams | ||||||||||||||||
| Amoxicillin | 32 | 0.125 | >4,096 | 64 | 1,024 | 2 | – | – | 2,048 | 32 | – | – | 2,048 | 128 | – | – |
| Ampicillin | 16 | 0.125 | >4,096 | 64 | 128 | 0.125 | – | – | 256 | 64 | 32 | <0.015 | 512 | 64 | 64 | 32 |
| Penicillin | – | – | – | – | – | – | – | – | – | – | – | – | 4,096 | 0.125 | 128 | 2 |
| Cephalosporins | ||||||||||||||||
| Ceftazidime | 0.125 | 0.03 | 512 | 512 | 1 | <0.015 | 0.5 | <0.015 | 1 | 0.125 | 2 | <0.015 | 0.5 | 0.06 | 16 | <0.015 |
| Ceftriaxone | 0.5 | <0.015 | 2,048 | 2,048 | <0.015 | <0.015 | 32 | 0.125 | 0.5 | 0.125 | 16 | <0.015 | 1 | 0.25 | 2 | <0.015 |
| Glycopeptides | ||||||||||||||||
| Vancomycin | – | – | – | – | – | – | – | – | – | – | – | – | 512 | 64 | 4 | 0.125 |
| Quinolones | ||||||||||||||||
| Ciprofloxacin | <0.015 | <0.015 | 16 | 4 | <0.015 | <0.015 | 0.06 | <0.015 | <0.015 | <0.015 | 0.25 | 0.25 | <0.015 | <0.015 | – | – |
| Tetracyclines | ||||||||||||||||
| Doxycycline | 8 | <0.015 | 64 | 0.5 | 32 | <0.015 | – | – | 64 | <0.015 | 64 | <0.015 | 32 | 4 | – | – |
| Tertacycline | 8 | <0.015 | 64 | 0.5 | 32 | <0.015 | – | – | 128 | 0.06 | 128 | 0.5 | 16 | 2 | 1 | <0.015 |
| Others | ||||||||||||||||
| Chloramphenicol | 32 | 0.06 | – | – | 64 | 0.125 | – | – | 128 | <0.015 | 128 | <0.015 | 4,096 | 1024 | 4 | 0.5 |
| Trimethoprim | 0.25 | 0.25 | 64 | 0.5 | 0.125 | <0.015 | – | – | 4,096 | 4 | 16 | <0.015 | 2 | 0.5 | 4 | <0.015 |
Notes: All experiments were repeated twice, and the higher of the two values was recorded. Columns A and B represent the MBC values of antibiotics and antibiotics in presence of AgNPs, respectively, for each pathogen.
Abbreviations: MBC, minimum bactericidal concentration; AgNP, silver nanoparticle.