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. 2013 Nov 6;14:763. doi: 10.1186/1471-2164-14-763

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Copyright © 2013 Pedroni et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Global distribution of differentially regulated transcripts in virulent and attenuated L17 Babesia bovis strain pair and the breakdown of the putative functions of these transcripts. (A) A total of 182 (116 + 66) genes were differentially expressed where 64% and 46% were upregulated in the virulent and attenuated strains, respectively. (B) Distribution of upregulated genes in the virulent strain and their putative protein functions. (C) Distribution of upregulated genes in the attenuated derivative strain and their putative functions. Ves, gene encoding for the variant erythrocyte surface antigen (VESA)1; sbp2, gene encoding for spherical body protein 2; smORF, gene encoding for the small open reading frame protein; misc., miscellaneous genes of various putative functions (as listed in Additional file 1: Table S4-S7).