Table 2.

Genes With Higher Transcript Levels in Older Men Than in Older Women and Their Transcriptional Changes With Aging for Each Sex

Gene Symbol	Older Men vs Older Women		Older Women vs Young Women		Older Men vs Young Men
	Fold	p	Fold	P	Fold	p
Mitochondrial structure and function
ATP5D	1.62	.023	−2.01	.001	−1.37	.018
ATP5G1	1.43	.040	−1.48	.004	−1.03	.712
COX6B1	1.22	.036	−1.25	.007	1.08	.199
COX8A	1.34	.023	−1.46	.001	−1.08	.307
CYC1	1.45	.047	−1.63	.001	−1.27	.004
DHRS4	1.38	.009	−1.34	.003	1.12	.253
MRPL24	1.26	.007	−1.39	<.001	−1.08	.200
MRPL34	1.36	.048	−1.41	.001	−1.19	.171
MRPS30	1.36	.038	−1.63	<.001	−1.39	<.001
MRPS7	1.36	.012	−1.41	.002	−1.05	.591
NDUFA11	1.27	.004	−1.44	<.001	−1.12	.066
NDUFS3	1.51	.012	−1.36	.012	1.04	.663
NDUFV3	1.50	.040	−1.68	<.001	1.03	.793
PDK2	1.43	.025	−1.53	.004	−1.17	.031
PGAM2	2.35	.017	−1.58	.060	1.32	.003
PHKG1	2.01	.023	−1.63	.074	−1.08	.320
SLC25A11	1.44	.025	−1.65	.003	−1.10	.441
SLC25A12	1.85	.007	−1.59	.012	−1.02	.805
SLC25A25	1.70	.004	−2.06	<.001	−1.02	.888
UCP3	2.23	.013	−1.87	.040	−1.31	.173
PPARGC1A	1.72	.063	−1.78	.020	−1.02	.941
Gene transcription and translation
RPLP0	1.32	.002	−1.15	.022	1.08	.257
RPLP0-like	1.44	.002	−1.25	.008	1.09	.306
EEF1A2	1.54	.040	−2.00	.001	−1.48	.002
EEF1B2	1.23	.054	1.02	.806	1.53	<.001
FAU	1.26	.018	−1.06	.593	1.22	.009
BATF2	1.42	.026	−1.35	.049	1.12	.129
HSF2	2.30	.001	−2.18	.008	1.17	.463
IKBKB	1.45	.025	−1.51	.001	−1.27	.113
GCN1L1	1.18	.036	1.04	.513	1.24	.031
MEX3B	1.44	.003	−1.12	.038	1.29	.005
MIF4GD	1.26	.041	−1.32	.003	−1.09	.266
NCOA3	1.62	.014	1.22	.273	1.68	.035
RBM15	1.36	.003	−1.03	.808	1.42	.006
RBM18	1.45	.009	−1.40	.006	1.08	.376
RBM9	1.44	.017	1.06	.712	1.42	.014
RPL3L	1.80	.032	−1.48	.048	1.21	.053
RPL4	1.15	.033	1.1	.148	1.27	.006
RPLP0	1.32	.002	−1.15	.022	1.08	.257