Table 1.

Amino acid sequence identity of the structural components of the V1V2 region for the chimeras

chimeras	V1	V2	β-A	V1 loop	β-B	connect	β-C	V2 loop	β-D
A/B	52.5	50.0	100.0	36.7	100.0	33.3	54.5	38.5	60.0
A/C	46.9	63.0	85.7	31.8	77.8	100.0	72.7	42.9	80.0
A/G	38.2	56.5	100.0	12.5	100.0	66.7	45.5	38.1	100.0
B/C	37.5	54.5	85.7	23.3	77.8	33.3	81.8	33.3	40.0
B/G	42.5	52.5	100.0	23.3	100.0	33.3	72.7	20.0	60.0

Results are based on the structure described in reference [31]. The values of sequence identity are given in percentage. The individual regions are defined as in Figure 1A. The similarity table based on the Blosum62 matrix is provided in Additional file 1: (Table S1).