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. Author manuscript; available in PMC: 2014 Aug 27.
Published in final edited form as: Langmuir. 2013 Aug 15;29(34):10.1021/la402214p. doi: 10.1021/la402214p

Figure 2.

Figure 2

(a) Circular dichroism spectra of quadruplex 2 (black), porphyrin 3 (blue), and a mixture of 2 and 3 (red) in potassium containing buffer (80 mM KCl, 10 mM Tris-HCl, pH 7.5). (b) Cryo-TEM image of assembly 4 in 160 mM KCl, 10 mM Tris-HCl, pH 7.5. Note: The concentrations of quadruplex 2 and porphyrin 3 for these studies were both 4 µM. (c) A representative model of a section of nanowire 4 (composed of two molecules of porphyrin 3 and one molecule of quadruplex 2). This model is based on the X-ray structure of the core quadruplex sequence (d[TGGGGT]4); PDB code 1S45. Note: the space-filled atoms are the adamantane binding units. The structure on the Left is a side view and structure on the Right is a top-view. The model was energy minimized (AMBER94 forcefield) using the MOE software. Note: This model is only a depiction and not a rigorous calculation.