Table 2. The association between serum uric acid (mg/dL) and decline in estimated glomerular filtration rate (ml/min per 1.73 m²).

	Minimally adjusted Model**				Multivariate adjusted Model†
	N	Annual decline	95% CI *	P-value	N	Annual decline	95% CI	P-value
Total population	2601	0.19	0.13, 0.26	1.2×10−10	2312	0.18	0.10, 0.26	1.0×10−5
Normotensive	1312	0.13	0.03, 0.23	0.008	1167	0.14	0.03, 0.25	0.014
Hypertensive	1275	0.24	0.14, 0.33	7.8×10−9	1145	0.20	0.08, 0.31	0.001
P for interaction				0.020				0.046

^*CI: confidence interval.

^**Adjusted for age, sex, and baseline eGFR.

^†Adjusted for age, sex, systolic blood pressure, body mass index, alcohol consumption, smoking, high density lipoprotein, diabetes mellitus, coronary heart disease, total cholesterol, and the use of diuretics, beta blockers, calcium channel blockers, ACE inhibitors, and baseline eGFR.