Table 2. Formation of tumors by cell populations with stem/non-stem cell phenotypes.
Cell phenotypes | # of cells transplanted to 3or 4 separate fat pads/mouse | % mice with tumor | Cell phenotypes | # of cells transplanted to 3or 4 separate fat pads/mouse | % mice with tumor |
SP | 6000 | 100 | ALDH1+ | 24000 | 50 |
SP | 3000 | 100 | ALDH1+ | 10000 | 50 |
SP | 1000 | 100 | ALDH1+ | 6000 | 33 |
SP | 500 | 100 | ALDH1+ | 3000 | 0 |
SP | 200 | 100 | ALDH1+ | 1000 | 0 |
SP | 50 | 67 | |||
SP | 25 | 0 | |||
Non-SP | 6000 | 100 | ALDH1− | 24000 | 50 |
Non-SP | 3000 | 100 | ALDH1− | 10000 | 25 |
Non-SP | 1000 | 100 | ALDH1− | 6000 | 25 |
Non-SP | 500 | 100 | ALDH1− | 3000 | 33 |
Non-SP | 200 | 0 | ALDH1− | 1000 | 0 |