Table 2. PISA analysis of the peptidase and propeller domain interface in the open and closed states of TbOPB, ApPREP and ApAAP.
TbOPB | ApPREP | ApAAP | ||||
Number of Residues | 715 | 690 | 659 | |||
Molecular Weight (kDa) | 80.7 | 76.5 | 73.9 | |||
Closed Structure (4BP9) | Open Structure (4BP8) | Closed Structure (3IVM) | Open Structure (3IUN) | Closed Structure (2HU8) | Open Structure (3O4J) | |
Buried Surface Area (Å2) | 2160 | 1218 (56%) | 2325 | 1061 (46%) | 2067 | 1050 (51%) |
Hydrogen Bonds | 30 | 14 (47%) | 26 | 9 (35%) | 49 | 19 (39%) |
Salt Bridges | 8 | 5 (62%) | 5 | 0 (0%) | 14 | 2 (14%) |
PDB codes for the analyses are shown. These are the same as those used in Fig. 3.