Figure 5. Timeline plots of the β3 secondary structure.

Illustrated are the WT form (A, C) and the P163S mutated form (B, D) either associated with αIIb (A, B) or αv (C, D) subunits. Shown are molecular dynamics time and primary sequence: time (60 ns) is on the horizontal axis and primary sequence is on the vertical axis. The following color code is used for the secondary structure: dark green = turn, yellow = β-sheet, pink = α-helix, blue = 3–10 helix, red = pi-helix, white = random. Position 163 is indicated by red arrows and the region concerned by the major changes is framed with a dotted box.