Table 1. Hydrogen bond changes in the different models.

	αIIbβ3 WT	αvβ3 WT	αIIbβ3 P163S	αvβ3 P163S
Average number
H-bonds (inter)	5.28	4.05	5.86	5.73
H-bonds (intra)	150.5	155.6	144.6	152.9
Global	155.78	159.65	150.46	158.63
% change vs WT αIIbβ3
H-bonds inter		−23.3%	11.0%
H-bonds intra		3.4%	−3.9%
Global		2.5%	−3.4%
% change vs WT αvβ3
H-bonds inter				41.5%
H-bonds intra				−1.7%
Global				−0.6%

Average number of (inter-, intra- or global) H-bonds found during the last 6 ns of the molecular dynamics simulations.