Figure 5. BCG ΔureC::hly_hIL7 and BCG ΔureC::hly_hIL18 emulate the protective efficacy of BCG ΔureC::hly.
A. Experimental design for protection study. B. Protective efficacy of BCG ΔureC::hly_hIL7 and BCG ΔureC::hly_hIL18 in a murine aerosol challenge model of M. tuberculosis. Shown are means ± SEM (n = 6–8 mice per group) analyzed using one-way ANOVA and Tukey’s post-hoc test; *p<0.05; **p<0.01 ***p<0.001. Experiment was performed twice.