Table 2. Comparison of the icELISA and HPLC method for quantitation of artemether in commercial drugs.
Druga | Batch No. | ELISA | HPLC |
Artemether injection (Kunming Pharma. Corp.) | 99125822 | 1.96±0.02b | 1.97±0.08b |
20000355.29 | 1.95±0.12 | 2.01±0.07 | |
20011052.01 | 2.08±0.06 | 2.07±0.05 | |
07CM01 | 2.05±0.01 | 2.00±0.03 | |
10 ML02 | 2.14±0.10 | 2.23±0.01 | |
Artemether soft capsules (Chongqing Holley Healthpro Pharmaceutical Co., Ltd.) | 20110301 | 2.18±0.11 | 2.12±0.04 |
Coartem 20/120 (Beijing Novartis Pharma Ltd.) | X1475 | 2.10±0.01 | 2.09±0.03 |
Co-Falcinum (Cipla Ltd.) | B/NK 01885 | 1.95±0.14 | 2.00±0.06 |
Each sample was analyzed in triplicate.
Data represent mean ± SD. The unit for ELISA and HPLC data was mg mL−1. The theoretical content of all drugs was 2 mg mL−1.