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. 2013 Nov 13;8(11):e79190. doi: 10.1371/journal.pone.0079190

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© 2013 Kingma et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Left panel: CTR (closed symbols; y = 32.4−112.6X, r² = 0.203) versus PC (open symbols; y = 11.6−32.9X, r² = 0.055) dogs. Middle panel: CTR (closed symbols; y = 32.4−112.6X, r² = 0.203) versus CD (open symbols; y = 24.9−96.4X, r² = 0.327). Right panel: CD (closed symbols; y = 24.9−96.4X, r² = 0.327) versus CD+PC (open symbols; y = 15.5−60.7X, r² = 0.079) dogs. The downward shift of the regression indicates significant protection that occurs independently of changes in coronary collateral blood flow. Each point represents an individual dog.