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. 2013 Nov 13;8(11):e79169. doi: 10.1371/journal.pone.0079169

Figure 1. Hepatic glycogenolysis.

Figure 1

Simplified representation of the pathway leading to the breakdown of glycogen into glucose in vertebrate liver. Protein kinase A (PKA) and its catalytic subunit (PKAc), glycogen phosphorylase kinase (PhK), glycogen phosphorylase (GPb and GPa) are the main enzymes involved in this process. The pathway involves a phosphorylation cascade, leading to glycogen breakdown. Inactive or dephosphorylated enzymes are italicized. Enzymes assayed in this study are inside grey boxes.