Table 3. Lytic spectrum of IME-EF1 and its endolysin.
Bacterial strain | Phage | Endolysin | Bacterial strain | Phage | Endolysin |
---|---|---|---|---|---|
E. faecalis 002 | + | + | E.faecium 065 | - | - |
E. faecalis 019 | + | + | E.faecium 081 | - | - |
E. faecalis 020 | + | + | E.faecium 106 | - | - |
E. faecalis 255 | - | + | E.faecium 137 | - | - |
E. faecalis 281 | - | + | E.faecium 271 | - | - |
E. faecalis 284 | - | + | E.faecium 289 | - | - |
E. faecalis 309 | - | + | E.faecium 322 | - | - |
E. faecalis 340 | - | + | E.faecium 327 | - | - |
E. faecalis V309 | - | + | S. aureus 037 | - | - |
E. faecalis V583 | - | + | S. aureus 047 | - | - |
E.faecium 010 | + | + | S. aureus 069 | - | - |
E.faecium 064 | - | - | S. aureus 086 | - | - |
V Vancomycin resistant + sensitive - insensitive
The 10 strains of multi-drug resistant E. faecalis and E. faecium, as well as three strains of multi-drug resistant S. aureus, isolated from a hospital were used to evaluate the lytic spectrum of IME-EF1 and its endolysin on BHI agar plate. V309 and V583 were the strains of Vancomycin-resistant E. faecalis.