Figure 6. Effects of various interventions on levels of Atg-12, LC3-II, and LAMP-2 in CD4 lymphocytes.

(A-C) Atg-12; (D-F) LC3-II; (G-I) LAMP-2; HIT, high-intensity interval training group (A, D, G); MCT, moderate continuous training group (B, E, H); CTL, control group (C, F, I); Pre, pre-intervention; Post, post-intervention; Rest, resting; HE, hypoxic (12%O₂) exercise test; Basal, untreated CD4 lymphocytes (Day 0); Vehicle and Rap, CD4 lymphocytes treated in the absence and presence of rapamycin (500nM) for 24 h (Day 1), respectively. *P<0.05, Rest vs. HE; +P<0.05, Pre vs. Post; ‡P<0.05, HIT or MCT vs. CTL. Values were mean±SE. n=10 in each group.