Table 1.
Bursting (n = 140) | Irregular (n = 77) | Regular (n = 46) | |
---|---|---|---|
Resting membrane potential (mV) | −74 ± 0.5 | −74 ± 0.6 | −76 ± 1 |
Input resistance (MΩ) | 60 ± 2 | 63 ± 3 | 59 ± 5 |
Membrane time constant (ms) | 9.8 ± 0.2 | 9.5 ± 0.4 | 9.3 ± 0.4 |
AP peak amplitude (mV) | 60 ± 1 | 55 ± 2 | 58 ± 2 |
AP threshold (mV) | −45 ± 0.6 | −43 ± 0.5 | −46 ± 1 |
AP width (ms) | 0.54 ± 0.01 | 0.56 ± 0.01 | 0.55 ± 0.02 |
AP time to peak (ms) | 0.44 ± 0.01 | 0.46 ± 0.01 | 0.46 ± 0.02 |
AHP amplitude (mV) | 15 ± 0.4 | 14 ± 0.5 | 13 ± 0.7 |
All values are means ± s.e.m. Input resistance and membrane time constant were measured on passive voltage responses to injection of negative current pulses (−100 pA, 500 ms). Action potentials (APs) were elicited by injection of suprathreshold current pulses (400 pA, 500 ms). AHP: afterhyperpolarization. AP time to peak and AHP were calculated using the spike threshold as a reference point.