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. 2013 Sep 18;143(12):1906–1912. doi: 10.3945/jn.113.180695

FIGURE 3.

FIGURE 3

Correlation network among milk glycans from women with, compared with those without, GDM selected by O-PLS-DA. Using Spearman’s ρ, P < 0.001, relations and strength of the relations (thickness of the lines; thickest lines, ρ = 0.97; thinnest lines, ρ = 0.5) among the milk components, represented by vertices, are annotated to show the relative difference and importance (vertex size, variable loading on LV1) of the glycans in milk from women with vs. without GDM (non-GDM). CH, complex hybrid; F, fucose; FS, fucose and sialic acid; GDM, gestational diabetes mellitus; HM, high mannose; LF, lactoferrin; LV, latent variable; O-PLS-DA, orthogonal signal corrected partial least-squares discriminant analysis; S, sialic acid; sIgA, secretory IgA; 5411, N-glycan containing 5 hexoses, 4 N-acetyl-hexosamines, 1 fucose, 1 sialic acid.