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. Author manuscript; available in PMC: 2013 Nov 14.
Published in final edited form as: Circulation. 2011 Jan 31;123(6):10.1161/CIRCULATIONAHA.110.973685. doi: 10.1161/CIRCULATIONAHA.110.973685

Figure 1. Deletion of mPGES-1 reduced neointimal formation.

Figure 1

Neointimal area (A), the ratio of intima to media (B) and stenosis (C) were reduced significantly in mPGES-1 KO mice compared to WT controls. (*: p<0.05; **: p < 0.01. n=4 per group for sham-operated animals; n=13 for WT injured animals; n=12 for KO injured animals). Representative H&E staining of cross sections from sham operated or wire-injured arteries is shown (D). N denotes neointima; M denotes media; ► indicates internal elastin; ◄ indicates external elastin. Scale bar denotes 20 µm.