Table 1.
Recommended dose of ENU for different inbred mouse strains, modified from Justice et al 2000 and Weber et al 2000.
| Inbred mouse strain | Recommended Dose (mg/kg) | No. days of sterility | Percent regained fertility |
|---|---|---|---|
| A/J | 3 ×90 | 74-113 | 90%(n=10) |
| BALB/cJ | 3 × 100 | 89-154 | 83% (n=6) |
| BTBR/N | 1 × 150-200 | 70-210 | 50-83% (ND) |
| C3He/J | 3 × 85 | 96-148 | 70%(n=10) |
| C3HeB/FeJ | 3 × 75 | 89-142 | 90%(n=10) |
| C57BL/6J | 3 × 100 | 90-105 | 80%(n=10) |
| FVB/N | 1 × 150 | 147 | 75% (n=4) |
The doses are recommended based on the least amount of death and shortest period of sterility. For details and alternate doses, see the original papers.