Table 2.

Comparison of RR Estimates from the BCRAT and the WHI

BCRAT risk category	BCRAT	WHI Hispanic		WHI non-Hispanic White
	RR	RR [95% CI]	P †	RR [95% CI]	P ‡
Age at menarche	1.10	1.08 [0.85, 1.37]	0.905	1.07 [1.03, 1.11]	0.230
Number of breast biopsies	1.27	1.71 [1.31, 2.24]	0.031	1.27 [1.22, 1.33]	0.994
Age at first live birth (AFB)	1.24	0.97 [0.78, 1.20]	0.024	1.13 [1.09, 1.18]	<0.001
Number of first-degree relatives  with breast cancer (FDR)	2.61	2.16 [1.13, 4.13]	0.571	1.31 [1.15, 1.49]	<0.001
AFB * FDR interaction	0.83	0.84 [0.55, 1.29]	0.925	1.01 [0.94, 1.09]	<0.001

Parameter estimates are Relative Risks (RRs), based on follow-up through the end of WHI Main study only; RR estimates based on comparisons to the referent category for each variable: Age at menarche (≥14 years old); Number of breast biopsies (0 biopsies); Age at first live birth (<20 years old); Number of first-degree relatives with breast cancer (0 relatives); AFB * FDR (<20 years old and 0 relatives)

^†Test of difference between WHI Hispanic and Gail Hispanic parameter estimates

^‡Test of difference between WHI White and Gail White parameter estimates