Table 3.

Dose, duration, and side effects of colistin, and treatment results

Dose in patients without renal failure (mg/kg)		4.90 ± 0.5
Duration (day)		19.8 ± 10.3 (4–62)
● Favorable outcome	23.1 ± 10.0 (8–62)
● Poor outcome or discontinuation of therapy	11.8 ± 5.6 (4–22)
Side effects (renal function impairment)		3 (7.3%)
Using of sedative or analgesic agents during the colistin treatment		28 (68.3%)
Concomitants nephrotoxic agent use		34 (82.9%)
Common nephrotoxic agents used with colistin
● Glycopeptides	23 (56.1%)
● Aminoglycosides	14 (34.1%)
● Furosemide	11 (26.8%)
● Amphotericin B	10 (24.4%)
● Antiviral agent (acyclovir)	1 (2.4%)
● Radiocontrast	1 (2.4%)
Result of treatment:
● Survey		29 (70.7%)
○ Clinical and microbiological response	28
○ Discontinuation of treatment due to side effect	1
● Exitus		12 (29.3%)
○ Infection related death	6
○ Infection unrelated death	6