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. Author manuscript; available in PMC: 2013 Nov 14.
Published in final edited form as: Am J Transplant. 2011 Aug 9;11(9):10.1111/j.1600-6143.2011.03623.x. doi: 10.1111/j.1600-6143.2011.03623.x

Figure 1. Acute cellular rejection following MHC-mismatched orthotopic lung transplant is associated with a decreased graft CD4:CD8 ratio.

Figure 1

(A) Gross pathology of BALB/c → B6 allograft and B6 →B6 isograft (graft left in photos) and (B) lung histology with H&E staining (10×) at day 10. (C) Acute rejection pathology score means at day 10 in isografts versus allografts (n=4 mice per group). (D) Comparison of mean mononuclear cell recovery at day 10 in isografts versus allografts (n=3–8 mice per group). (E) Mean lung graft CD4:CD8 ratio determined by flow cytometry in isografts versus allografts (n=3–8 mice per group).