Table 6.
Estimated preference weights and Willingness to Pay (WTP) in a propensity score matched subset of the public and patients
| |
The public, scenario A |
|
(N = 83) |
patients, scenario A |
|
(N = 38) |
P-value for difference |
|---|---|---|---|---|---|---|---|
| Coefficient (s.e.) | OR | MWTP | Coefficient (s.e.) | OR | MWTP | ||
|
Untreated responders& |
|
|
|
|
|
|
|
| 5% |
0.248 (0.0687)** |
1.58 |
2,658 |
0.8794 (0.1068)** |
5.23 |
12,820 |
<.0001 |
| 20% |
0.0528 (0.0676) |
1.30 |
1517 |
0.0442 (0.1068) |
2.27 |
6,346 |
0.6084 |
| 35% |
−0.0942 (0.0702) |
1.12 |
657 |
−0.1492 (0.1133) |
1.87 |
4,847 |
0.6582 |
| 50% |
−0.2066 |
1 |
Ref |
−0.7744 |
1 |
Ref |
|
|
Unnecessary treatment of non-responders† |
|
|
|
|
|
|
|
| 5% |
0.1867 (0.0679)** |
1.39 |
1,919 |
0.1083 (0.1083) |
1.59 |
3,580 |
0.9663 |
| 20% |
0.0134 (0.0697) |
1.17 |
906 |
0.2391 (0.1112)* |
1.81 |
4,594 |
0.1598 |
| 35% |
−0.0586 (0.0683) |
1.09 |
485 |
0.0062 (0.1088) |
1.43 |
2,789 |
0.657 |
| 50% |
−0.1415 |
1 |
Ref |
−0.3526 |
1 |
Ref |
|
|
Severity of side effects |
|
|
|
|
|
|
|
| Mild |
0.2712 (0.0524)** |
2.10 |
4,327 |
0.3084 (0.0839)** |
2.09 |
5,716 |
0.7 |
| Moderate |
0.1976 (0.053)** |
1.95 |
3,897 |
0.1206 (0.0871) |
1.73 |
4,260 |
0.3008 |
| Severe |
−0.4688 |
1 |
Ref |
−0.4290 |
1 |
Ref |
|
|
Likelihood of side effects |
|
|
|
|
|
|
|
| 5% |
0.2645 (0.0521)** |
1.65 |
2,937 |
0.2735 (0.0838)* |
1.60 |
3,650 |
0.8119 |
| 50% |
−0.0267 (0.0529) |
1.24 |
1,235 |
−0.0762 (0.0864) |
1.13 |
939 |
0.5678 |
| 95% |
−0.2378 |
1 |
Ref |
−0.1973 |
1 |
Ref |
|
|
Genetic test turnaround time |
|
|
|
|
|
|
|
| 2 days |
0.1673 (0.0531)** |
1.40 |
1,978 |
0.0174 (0.087) |
1.15 |
1,117 |
0.2467 |
| 7 days |
0.0036 (0.0521) |
1.19 |
1,021 |
0.1093 (0.0857) |
1.27 |
1,829 |
0.5259 |
| 12 days |
−0.1709 |
1 |
Ref |
−0.1267 |
1 |
Ref |
|
|
Genetic test procedure |
|
|
|
|
|
|
|
| Mouth swab |
0.2591 (0.0783)** |
1.75 |
3,258 |
0.3918 (0.1239)* |
2.43 |
6,881 |
0.4303 |
| Blood sample |
0.3382 (0.0825)** |
1.89 |
3,720 |
0.1168 (0.1322) |
1.85 |
4,750 |
0.2508 |
| Tumor biopsy |
−0.04 (0.0828) |
1.29 |
1,509 |
−0.0829 (0.1342) |
1.51 |
3,202 |
0.7787 |
| Bone marrow biopsy |
−0.2593 (0.081)** |
1.04 |
226 |
0.0702 (0.1286) |
1.76 |
4,388 |
0.1121 |
| Liver biopsy |
−0.2980 |
1 |
Ref |
−0.4959 |
1 |
Ref |
|
|
Neither (No test) |
−1.0346 (0.1037)** |
0.36 |
−6,050 |
−0.1185 (0.1382) |
0.89 |
−919 |
0.0002 |
|
Genetic test cost |
−0.00017 (0.00007)* |
|
Ref |
−0.00013 (0.00012) |
|
Ref |
0.1901 |
| McFadden’s LRI |
0.20 |
|
|
|
|
|
|
| Adjusted Estrella |
0.35 |
|
|
|
|
|
|
| Log-likelihood Ratio |
832.8 |
|
|
|
|
|
|
| AIC |
3493 |
|
|
|
|
|
|
| Schwartz Criterion | 3694 |
** p-value < 0.01; * p-value < 0.05.
&1-Sensitivity.
†1-specificity.