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. 2013 Oct 16;10:106. doi: 10.1186/1742-4690-10-106

Figure 5.

Figure 5

Elevated expression of restriction factor genes in HIV-1 elite controllers with respect to ART-suppressed individuals. Five restriction factors were significantly elevated in elite controllers with respect to ART-suppressed subjects: (A) APOBEC3C, (B) APOBEC3D, (C) CTR9, (D) TRIM26, and (E) TRIM32. Gene expression between groups was compared using unpaired t tests. (F) The expression of CDKN1A/p21 was positively correlated with CD4+ T cell activation in elite controllers. There were no correlations between gene expression and activation in ART-suppressed individuals. Correlations were evaluated using Pearson’s r tests.