Table 1.
Demographic information and tumor characteristics of patients included in genotyping ancillary study
| |
Overall sample |
Sex stratified |
Race stratified |
||
|---|---|---|---|---|---|
| N = 279 | Male (n = 142) | Female (n = 137) | White (n = 229) | Other (n = 50) | |
|
Age: Median (range) |
58.0 (18 – 85) |
57.0 (18 – 85) |
58.0 (18 – 81) |
59.0 (18 – 85) |
53.0 (27 – 78) |
|
Sex: N (%) |
|
|
|
|
|
| Male |
142 (51) |
--- |
--- |
--- |
--- |
| Female |
137 (49) |
--- |
--- |
--- |
--- |
|
Race: N (%) |
|
|
|
|
|
| White |
229 (82) |
122 (86) |
107 (78) |
--- |
--- |
| Other |
50 (18) |
20 (14) |
30 (22) |
--- |
--- |
|
Tumor Size: Median (range) |
6.5 (3.0 – 37.0) |
6.0 (3.0 – 37.0) |
6.5 (3.0 – 28.0) |
6.5 (3.0 – 37.0) |
6.0 (3.1 – 30.0) |
|
Tumor Size: N(%) |
|
|
|
|
|
| <5 cm |
79 (28) |
41 (29) |
38 (28) |
65 (28) |
14 (28) |
| 5-10 cm |
146 (52) |
72 (51) |
74 (54) |
119 (52) |
27 (54) |
| >10 cm |
54 (19) |
29 (20) |
25 (18) |
45 (20) |
9 (18) |
|
Mitotic Rate: Median (range) |
3 (0 – 351) |
3 (0 – 351) |
3 (0 – 207) |
3 (0 – 351) |
4.5 (0 – 81) |
|
Mitotic Rate: N(%) |
|
|
|
|
|
| <5 |
156 (60) |
77 (58) |
79 (63) |
132 (62) |
24 (50) |
| ≥5 |
104 (40) |
57 (42) |
47 (37) |
80 (38) |
24 (50) |
| Missing |
19 |
8 |
11 |
17 |
2 |
|
Tumor Location: N(%) |
|
|
|
|
|
| Stomach |
182 (66) |
97 (69) |
85 (63) |
146 (64) |
36 (74) |
| Small Intestine |
85 (31) |
39 (28) |
46 (34) |
77 (34) |
8 (16) |
| Rectum |
2 (1) |
1 (1) |
1 (1) |
1 (0) |
1 (2) |
| Other |
8 (3) |
4 (3) |
4 (3) |
4 (2) |
4 (8) |
| Missing |
2 |
1 |
1 |
1 |
1 |
|
Mutation Type: N(%) |
|
|
|
|
|
| Exon 9 |
15 (5) |
9 (6) |
6 (4) |
15 (7) |
0 (0) |
| Exon 11 |
195 (70) |
95 (67) |
100 (73) |
153 (67) |
42 (84) |
| Exon 13 |
3 (1) |
0 (0) |
3 (2) |
2 (1) |
1 (2) |
| Exon 14 |
1 (0) |
1 (1) |
0 (0) |
1 (0) |
0 (0) |
| Exon 17 |
0 (0) |
0 (0) |
0 (0) |
0 (0) |
0 (0) |
| PDGFRA |
29 (10) |
21 (15) |
8 (6) |
25 (11) |
4 (8) |
| Wild type |
36 (13) |
16 (11) |
20 (15) |
33 (14) |
3 (6) |
|
Exon 11 mutation type: N(%) |
|
|
|
|
|
| 557-558 deletion |
66 (34) |
33 (35) |
33 (33) |
51 (33) |
15 (36) |
| Other deletion |
45 (23) |
25 (26) |
20 (20) |
34 (22) |
11 (26) |
| Insertion |
28 (14) |
14 (15) |
14 (14) |
23 (15) |
5 (12) |
| Point Mutation |
56 (29) |
23 (24) |
33 (33) |
45 (29) |
11 (26) |
|
PDGFRA mutation type: N(%) |
|
|
|
|
|
| D842V |
12 (41) |
10 (48) |
2 (25) |
10 (40) |
2 (50) |
| Other | 17 (59) | 11 (52) | 6 (75) | 15 (60) | 2 (50) |