Table 3.
BF (Competing Risks) | DM (Competing Risks) | OM (Cox) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Covariate | Groups | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value |
RT Dose | <75 Gy | Ref | Ref | Ref | ||||||
75-79.9 Gy | 0.91 | 0.46-1.80 | 0.795 | 0.37 | 0.13-1.03 | 0.058 | 0.80 | 0.42-1.54 | 0.509 | |
≥80 Gy | 0.28 | 0.10-0.74 | 0.011 | 0.09 | 0.01-0.52 | 0.007 | 0.42 | 0.19-0.94 | 0.035 | |
PSA | <10 | Ref | Ref | Ref | ||||||
10-20 | 0.61 | 0.25-1.45 | 0.262 | 0.38 | 0.08-1.84 | 0.228 | 1.40 | 0.71-2.75 | 0.333 | |
≥ 20 | 1.78 | 0.93-3.42 | 0.084 | 1.15 | 0.35-3.80 | 0.821 | 1.44 | 0.76-2.71 | 0.266 | |
T-category | T1 | Ref | Ref | Ref | ||||||
T2 | 1.07 | 0.38-3.03 | 0.900 | 0.62 | 0.12-3.25 | 0.570 | 1.25 | 0.57-2.75 | 0.584 | |
T3/T4 | 2.74 | 0.89-8.40 | 0.079 | 3.44 | 0.74-16.05 | 0.116 | 2.40 | 1.04-5.55 | 0.041 | |
TX | 0.68 | 1.07-4.28 | 0.679 | 0.78 | 0.03-17.91 | 0.879 | 0.68 | 0.14-3.38 | 0.641 | |
ADT | None | Ref | Ref | Ref | ||||||
< 6 mo | 0.72 | 0.26-1.95 | 0.511 | 0.37 | 0.06-2.30 | 0.286 | 0.77 | 0.33-1.79 | 0.536 | |
6-23 mo | 0.87 | 0.34-2.23 | 0.767 | 3.37 | 0.62-18.38 | 0.160 | 1.19 | 0.56-2.55 | 0.649 | |
≥24 mo | 0.38 | 0.15-0.92 | 0.033 | 1.10 | 0.26-4.62 | 0.892 | 0.63 | 0.29-1.39 | 0.254 | |
Age | 40-59 | Ref | Ref | Ref | ||||||
60-69 | 0.59 | 0.19-1.51 | 0.240 | 0.73 | 0.18-3.02 | 0.666 | 1.59 | 0.49-5.12 | 0.440 | |
70-79 | 0.46 | 0.16-1.33 | 0.153 | 0.50 | 0.10-2.54 | 0.406 | 2.68 | 0.90-8.00 | 0.078 | |
80-89 | 1.19 | 0.27-5.27 | 0.815 | 1.14 | 0.14-9.17 | 0.902 | 2.78 | 0.64-12.04 | 0.171 | |
Technique | Conventional | 0.61 | 0.17-2.18 | 0.451 | 0.63 | 0.12-3.32 | 0.584 | 1.03 | 0.36-2.92 | 0.954 |
3DCRT | Ref | Ref | Ref | |||||||
IMRT | 0.63 | 0.21-1.92 | 0.420 | 1.10 | 0.30-4.06 | 0.887 |
For technique, the referent group was 3DCRT except for the distant metastasis (DM) endpoint, where 3DCRT and IMRT were combined due to the small number of events. Other abbreviations: Prostate specific antigen (PSA), androgen deprivation therapy (ADT), palpation tumor category (T-category), radiation therapy (RT), intensity modulated RT (IMRT), 3D conformal RT (3DCRT)