ANDb/b TCR Tg and ANDk/k TCR Tg mice, plus their respective B6 and B10.BR control groups, were infected with LP-BM5 and studied in parallel. Disease parameters were assayed 10 weeks p.i., and shown here are one activational parameter: spleen weight (A), and one immunodeficiency parameter: mitogen response to LPS (B), with all other parameters clearly demonstrating that B6, ANDb/b TCR Tg, and B10.BR mice are MAIDS susceptible but ANDk/k TCR Tg mice are MAIDS resistant. The results were significant (*, P < 0.05) or not significant (NS, P ≥ 0.05). This experiment has been performed a total of three times, with the same pattern of results consistently obtained.