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. Author manuscript; available in PMC: 2013 Nov 14.
Published in final edited form as: J Mol Cell Cardiol. 2012 May 15;53(2):10.1016/j.yjmcc.2012.05.004. doi: 10.1016/j.yjmcc.2012.05.004

Figure 1. Acute ACF induces FA signaling downregulation.

Figure 1

(A) Top, Representative picrosirius red staining.(Bar = 40 μM) Bottom, Interstitial collagen accumulation as determined by morphometric analysis. (B–C) LV extracts from control and ACF operated rats were assessed for immunoblot analysis. Top, representative immunoblots (with each lane from a single gel exposed for the same duration). Bottom, fold induction, n=6 each group, *P<0.05 vs. sham. (D) LV lysates from sham or ACF animals were immunoprecipitated (IP) with anti-FAK antibodies and immunoblotted with anti-phosphotyrosine, p130Cas, paxillin or FAK antibodies.