Table 1. Mutations identified in 15 starved, nalidixic acid resistant isolates.
Location on the chromosome | Gene | Number of reads1 | Nucleotide change | Number of 15 strains carrying mutation2 | Position in protein | Amino acid change |
2337183 | gyrA | 399/954 | A to G | 7 | 87 | Asp to Gly |
2337184 | gyrA | 139/955 | G to T | 1 | 87 | Asp to Tyr |
2337195 | gyrA | 399/938 | C to T | 7 | 83 | Ser to Leu |
2557709 | intZ | 34/836 | T to C | 1 | 477 | Val to Ala |
Number of reads at which variant allele was called out of total number of reads at that position.
Based on PCR and Sanger re-sequencing from individual strains.