Table 3. Mutations identified in 15 non-starved and 15 starved isolates, untested for resistance.
Experiment | Location on the chromosome | Number of reads1 | Number of 15 strains carrying mutation2 | Nucleotide change | Mutation type |
Day 1 (no starvation) | 140082 | 29/1068 | 1 | C to A | SNP, Silent3 |
Starvation | 2758469 | 44/842 | 1 | C to T | SNP, Intergenic4 |
Starvation | 3246643 | 87/916 | 1 | T to G | SNP, Silent5 |
Starvation | 3948188 | 53/778 | 1 | T deletion | Indel, Intergenic6 |
Number of reads at which variant allele was called out of total number of reads at that position.
Based on PCR and Sanger re-sequencing from individual strains.
Located within the gene gcd.
Located between the genes yfjI and yfjJ.
Located within the gene mzrA.
Located between the genes yifB and ilvL.