Figure 2. ABR deficit in Df1/+ mice is often monolateral, and shows no age dependence.

(A) Click ABR thresholds recorded in left versus right ears, for WT (black) and Df1/+ (red) mice in which both ears were tested. Dashed line indicates criterion threshold for a significant click ABR deficit. (B) Click ABR thresholds versus age, for all ABR recordings. Solid lines indicate best-fit regression lines. Slopes were not significantly different from zero for recordings from either WT (black; slope 95% CI [-0.047, 0.072]) or Df1/+ (red; slope 95% CI [-0.072, 0.030]) animals. To ensure visibility of overlapped data points, zero-mean, 1 dB SPL standard-deviation Gaussian noise was added to threshold data in both A and B for display.