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. 2013 Nov 14;8(11):e80472. doi: 10.1371/journal.pone.0080472

Table 1. Pregnancy outcome after mice were exposed to different regimens of restraint stress during peri-implantation.

Restraint regimens Treatment No. of mice showing plugs* % Term pregnancy$ Litter size Birth weight of pups (g)
Regimen 1 Control 24 91.7±4.2a 9.2±0.8a 1.74±0.05a
Stressed 24 79.2±4.2a 9.0±1.1a 1.73±0.04a
Regimen 2 Control 24 95.8±4.2a 11.0±0.7a 1.80±0.03a
Stressed 24 41.7±4.2b 4.5±1.2b 1.88±0.06a
Regimen 3 Control 24 91.7±4.2a 9.7±0.9a 1.76±0.02a
Stressed 24 62.5±12.5a 6.7±1.2a 1.67±0.06a
a–b

: Values without a common letter in their superscripts differ (P<0.05) in the same column within stress regimens.

*Each treatment was repeated 3 times and each replicate contained data from 8 mice.

$

In this paper, % Term pregnancy refers to the ratio of mice giving birth/mice showing vaginal plugs, and Independent samples t-tests were conducted using SPSS to compare the effects of different regimens of restraint stress on term pregnancy.