Table 1. Characteristics of study mice.

Infusions	Saline		AngII
	Vehicle	Amlodipine	Vehicle	Amlodipine
n	10	10	7*	10
Body weight (g)	28.0 ± 0.5	27.6 ± 0.5	26.9 ± 0.6	26.9 ± 0.5
Plasma cholesterol (mg/dl)	1038 ± 41	949 ± 41	1168 ± 49	1119 ± 41
Plasma renin (ng/ml/30 min)	3.0 ± 0.3	8.5 ± 1.3†	1.1 ± 0.1#	5.2 ± 1.1†#

Body weight, plasma cholesterol and renin concentrations were measured after 28 days of infusions. Values are represented as mean ± SEM. * Ten mice were initiated in the study, but 3 succumbed to aortic rupture, so data were derived from 7 surviving mice. ^† P<0.0001, compared to vehicle within saline or AngII groups. ^# P=0.005, compared to saline infusion within vehicle or amlodipine groups.