Table 3. Summary of inhibition of WOG and PTX on BGC-823 xenografts.
| Dose (mg/kg) | Body weight (g) |
Number of animals |
Tumor weight (g) | IR (%) | |||
|---|---|---|---|---|---|---|---|
| Incipience | Terminal | Incipience | Terminal | ||||
| Control | 22.1±0.8 | 23.9±0.7 | 5 | 5 | 2.72±0.28 | ||
| WOG =60 | 21.5±1.1 | 22.9±1.1 | 5 | 5 | 2.17±0.29* | 20.29 | |
| PTX =10 | 21.8±0.6 | 23.2±1.1 | 5 | 5 | 2.12±0.56* | 22.27 | |
| PTX =20 | 21.0±1.3 | 22.5±0.7 | 5 | 5 | 1.02±0.43** | 62.53 | |
| WOG + PTX =60+10 | 19.9±1.3 | 21.4±1.9 | 5 | 5 | 1.05±0.65**## | 61.58 | |
| WOG + PTX =60+20 | 20.9±1.4 | 21.4±0.8 | 5 | 5 | 1.01±0.21**# | 62.75 | |
IR, inhibitory ratio of tumor weight; *, P<0.05 compared with control; **, P<0.01 compared with control; ##, P<0.01 combination group compared with corresponding single-agent groups; #, P<0.01 combination group compared with WOG 60 mg/kg group.