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Longitudinal changes in rCBF. Regions showing differences in longitudinal rates of rCBF changes for the CI group relative to the CN group are shown on sagittal sections of the brain. Areas in yellow represent regions where CI show greater increases in rCBF over time relative to CN; areas in blue represent regions where CI exhibit greater decreases in rCBF over time. The group difference in insular decline (slice 4) did not remain significant after MRI tissue volume correction.
