Figure 2.
Selective PLCβ inhibition reduces IP3 levels in the striatum of WT and DAT-KO mice. WT and DAT-KO mice were treated with vehicle (VEH) or a selective PLCβ inhibitor, U73122 (10 mg/kg). IP3 levels were assessed using radioimmunoassay and were reported as a percentage of WT vehicle-treated mice. Data are presented as the mean ± SEM. N = 5. *p < 0.05, Student's t test.