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Human placental syncytiotrophoblast cells express markers of cellular senescence. H&E staining demonstrated general structure of the placenta. Sections of human post-partum third trimester placenta were evaluated for SA-β-gal activity (SA-β-gal), expression of ERVWE1, proliferation marker Ki67, and senescence markers p53, DCR2, p16, p21, and γH2AX. Arrowheads indicate syncytiotrophoblast cells.
