Table 4. Total and area-specific associations between air pollutants estimated to the birth address and health outcomes during the first 10 years of life.* .
| Total population | GINI/LISA South | GINI/LISA North | LISA East | |||||
|---|---|---|---|---|---|---|---|---|
| N | OR [95% CI] | N | OR [95% CI] | N | OR [95% CI] | N | OR [95% CI] | |
| NO2 | ||||||||
| Asthma | 4585 | 0.89 [0.73, 1.08] | 2524 | 0.86 [0.62, 1.18] | 1545 | 0.95 [0.77, 1.18] | 516 | 1.02 [0.69, 1.50] |
| Allergic rhinitis | 4586 | 0.96 [0.85, 1.09] | 2525 | 0.86 [0.71, 1.02] | 1545 | 1.10 [0.96, 1.26] | 516 | 1.18 [0.91, 1.54] |
| Eyes and nose symptoms | 4586 | 0.96 [0.87, 1.05] | 2525 | 0.90 [0.78, 1.04] | 1545 | 1.03 [0.92, 1.15] | 516 | 0.96 [0.75, 1.24] |
| Aeroallergen sensitization | 3013 | 0.92 [0.84, 1.01] | 1689 | 0.84 [0.73, 0.97] | 975 | 1.06 [0.93, 1.21] | 349 | 1.12 [0.86, 1.44] |
| PM 2.5 mass | ||||||||
| Asthma | 4585 | 0.97 [0.59, 1.58] | 2524 | 0.96 [0.74, 1.25] | 1545 | 0.89 [ 0.64, 1.23] | 516 | 1.06 [0.83, 1.35] |
| Allergic rhinitis | 4586 | 0.87 [0.60, 1.26] | 2525 | 0.89 [0.76, 1.06] | 1545 | 1.22 [0.99, 1.50] | 516 | 0.95 [0.81, 1.11] |
| Eyes and nose symptoms | 4586 | 0.93 [0.67, 1.29] | 2525 | 0.96 [0.84, 1.10] | 1545 | 1.19 [0.99, 1.43] | 516 | 0.93 [0.83, 1.05] |
| Aeroallergen sensitization | 3013 | 1.10 [0.83, 1.45] | 1689 | 1.01 [0.89, 1.14] | 975 | 1.14 [0.95, 1.37] | 349 | 1.03 [0.89, 1.19] |
| PM 2.5 absorbance | ||||||||
| Asthma | 4069 | 0.82 [0.55, 1.21] | 2524 | 0.94 [0.75, 1.18] | 1545 | 0.88 [0.67, 1.14] | - | - |
| Allergic rhinitis | 4070 | 0.75 [0.58, 0.96] | 2525 | 0.83 [0.72, 0.96] | 1545 | 1.00 [0.84, 1.20] | - | - |
| Eyes and nose symptoms | 4070 | 0.91 [0.75, 1.10] | 2525 | 0.93 [0.84, 1.04] | 1545 | 1.02 [0.88, 1.19] | - | - |
| Aeroallergen sensitization | 2664 | 0.82 [0.68, 0.99] | 1689 | 0.87 [0.78, 0.97] | 975 | 1.02 [0.89, 1.18] | - | - |
| Ozone | ||||||||
| Asthma | 4649 | 1.20 [0.98, 1.48] | 2569 | 1.05 [0.98, 1.13] | 1562 | 1.23 [0.78, 1.94] | 518 | 1.10 [0.86, 1.42] |
| Allergic rhinitis | 4650 | 1.02 [0.90, 1.16] | 2570 | 1.00 [0.96, 1.05] | 1562 | 0.92 [0.68, 1.27] | 518 | 1.30 [1.02, 1.64] |
| Eyes and nose symptoms | 4650 | 0.97 [0.87, 1.08] | 2570 | 1.00 [0.96, 1.03] | 1562 | 0.77 [0.57, 1.04] | 518 | 1.35 [1.16, 1.59] |
| Aeroallergen sensitization | 3049 | 0.99 [0.89, 1.09] | 1716 | 1.01 [0.98, 1.04] | 982 | 0.79 [0.61, 1.02] | 351 | 1.17 [0.96, 1.43] |
Notes.
Bold = statistically significant result (p-value < 0.05).
*
Odds ratios are calculated per interquartile increase of each air pollutant. Models are adjusted for sex, age, parental history of atopy, parental education, older siblings, maternal smoking during pregnancy, smoke exposure in the home, contact with furry pets, use of gas stove for cooking, home dampness or indoor mold, intervention participation, cohort and area (total models only).