Table 2. Amount of non-coding gene symbol in cellular and exosomal RNA based on 90% coverage over exons of non-coding transcripts.
In exosomes, the top 5 non-coding gene types including small nucleolar RNA, small nuclear RNA, Mt_tRNA, microRNA, and non-coding RNA represents about 90% of non-coding genes in both exosome samples.
| Gene type | MDA-MB-231 cellular (gene symbols) |
MDA-MB-231 exosomal (gene symbols) |
MDA-MB-436 exosomal (gene symbols) |
|---|---|---|---|
| small nucleolar RNA | 214 | 83 | 51 |
| small nuclear RNA | 23 | 11 | 10 |
| Mt_tRNA | 13 | 7 | 4 |
| microRNA | 34 | 6 | 2 |
| non-coding RNA | 42 | 1 | 0 |
| guide RNA | 20 | 0 | 1 |
| vault RNA | 3 | 0 | 3 |
| rRNA | 1 | 1 | 2 |
| RNase MRP RNA | 1 | 1 | 1 |
| RNase P RNA | 1 | 1 | 1 |
| Mt_rRNA | 1 | 1 | 0 |
| lincRNA | 1 | 0 | 0 |
| telomerase RNA | 1 | 0 | 0 |