Figure 1.

ClustalX primary sequence alignment of Synechocystis sp. PCC 6803 glutaredoxin A (3QMX) Kim et al., 2012, Grx4 from E. coli (1YKA) (Fladvad et al., 2005), Grx1 from Francisella tularensis (3MSZ), glutaredoxin domain from human glutaredoxin 3 (3ZYW), Grx domain from Mus thioredoxin reductase (2LV3) (Dobrovolska et al., 2012), Zebrafish Grx2 (3UIW) (Brautigam et al., 2013), glutaredoxin S12 from Poplar (3FZ9) (Couturier et al., 2009). The “*” above the sequence corresponds to mutations made and characterized within the protein. The arrow shapes represent beta-strand secondary structure; coils are regions of the protein in alpha-helical configuration. Letters in BOLD correspond to highly conserved features in all glutaredoxins proteins. Numbers in parentheses correspond to the residue numbers in the native protein sequence. Non-native residues were excluded from this alignment.