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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Adv Chronic Kidney Dis. 2013 Nov;20(6):10.1053/j.ackd.2013.06.001. doi: 10.1053/j.ackd.2013.06.001

Figure 3. Generation of C3d-targeted SPIO nanoparticles.

Figure 3

Iron-oxide crystals can be coated with various organic and inorganic polymers. Targeting molecules, such as recombinant complement receptor-2 (CR2) can be conjugated to the surface of the nanoparticles after they are coated, or incorporated into the polymer prior to encapsulating the SPIO. This is a figurative representation and does not accurately represent the scale of the final targeted SPIO.