. Author manuscript; available in PMC: 2013 Nov 15.

Published in final edited form as: J Clin Epidemiol. 2008 Nov 17;62(2):10.1016/j.jclinepi.2008.08.007. doi: 10.1016/j.jclinepi.2008.08.007

Table 1. Absolute and relative changes in level and trend of the monthly co-prescription rate (per 10,000 warfarin users) following alert changes, and associated 95% confidence intervals around these changes estimated with the multivariate delta and bootstrapping methods.

	Absolute Change [Exact]	Relative Change [Multivariate Delta Method]	Relative Change [Bootstrapping Method]
Total co-prescription
EMR alerts level to baseline level	-311.4 (-480.3,-142.4)	-9.5% (-14.7%,-4.4%)	-9.5% (-15.6%,-3.6%)
Six months after the EMR alerts	-439.1 (-543.6, -334.6)	-13.5% (-16.6%, -10.4%)	-13.5% (-17.8%, -8.6%)
Acetaminophen co-prescription
EMR alerts level to baseline level	-311.0 (-495.0,-127.0)	-13.4% (-21.6%,-5.3%)	-13.4% (-21.7%,-5.2%)
EMR alerts trend to baseline trend	-22.2 (-38.1,-6.3)	-267.5% (-475.7%, -59.3%)	-266.9% (-650.3%, -80.0%)
Six months after the EMR alerts	-444.2 (-598.4, -290.0)	-16.7% (-21.8%, -11.5%)	-16.7% (-21.7%, -11.3%)