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. 2013 Sep 13;2(11):1148–1159. doi: 10.1242/bio.20135090

Fig. 4. DDR1 over-expression enhances focal adhesion maturation.

Fig. 4.

(A) Cells plated overnight on collagen were immunostained for talin and imaged by TIRF microscopy. (B) Analysis with Metamorph shows increased numbers of talin-containing focal adhesions in DDR1 over-expressing compared to wild type cells (P<0.0001). (C) Cells plated overnight on collagen were immunostained for paxillin and imaged by TIRF microscopy. (D) DDR1 over-expressing cells exhibit increased numbers of paxillin-containing focal adhesions (P<0.0001). (E) Cells plated overnight on collagen were immunostained for vinculin and imaged by TIRF microscopy. (F) Increased numbers of vinculin-stained focal adhesions in DDR1 over-expressing cells (P<0.0001).