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. 2013 Aug 23;2(4):e000090. doi: 10.1161/JAHA.113.000090

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 2. — Spatial and temporal evolution of Wallerian degeneration in a single patient. Serial diffusion‐weighted imaging magnetic resonance images (MRIs) are shown for a single patient with a putaminal hemorrhage, obtained 2 days, 1 week, and 2 weeks after symptom onset. Corresponding fluid attenuated inversion recovery (FLAIR) sequences are shown at 3 months. A, Internal capsule. B, Cerebral peduncle. C, Pons. D, Medulla. Restricted diffusion appears along the ipsilateral corticospinal tract at 1 week in the posterior limb of the internal capsule, cerebral peduncle, and pons (arrows). At 2 weeks restricted diffusion appears in the medullary pyramid (arrow). At 3 months, areas that previously showed restricted diffusion are hyperintense on FLAIR and have undergone atrophy (arrows).