Table 2.
Sensitivity Analysis
| Variable | PCI | CABG | RR | P Value | Heterogeneity | |
|---|---|---|---|---|---|---|
| MACE based on SYNTAX Score* | <22 (n=805) | 22.2% | 17.5% | 1.27 (0.96 to 1.68) | 0.09 | 0%; P=0.32 |
| 23 to 32 (n=992) | 26.1% | 18.3% | 1.32 (0.86 to 2.02) | 0.21 | 48%; P=0.16 | |
| >33 (n=541) | 24.7% | 14.4% | 1.73 (1.21 to 2.46) | 0.003 | 0%; P=0.81 | |
| After excluding VA CARDS Trial | MACE (n=2854) | 22.4% | 16.7% | 1.34 (1.15 to 1.55) | 0.0002 | 0%; P=0.94 |
| Death (n=2854) | 13.5% | 9.9% | 1.36 (1.11 to 1.66) | 0.003 | 0%; P=0.53 | |
| MI (n=2854) | 10.6% | 5.3% | 2.01 (1.54 to 2.62) | <0.0001 | 0%; P=0.83 | |
| Repeat revascularization (n=2854) | 17.3% | 6.5% | 2.61 (2.09 to 3.2) | <0.00001 | 0%; P=0.89 |
PCI indicates percutaneous coronary intervention; CABG, coronary artery bypass graft surgery; RR, risk ratio; MACE, major adverse cardiac events; MI, myocardial infarction.
*
Pooled analysis (random‐effects model) from SYNTAX (5‐year follow‐up) and FREEDOM (5‐year follow‐up).