Table 2.
Spearman Correlations Between Biomarkers of Inflammation, Insulin Resistance, Adiposity, Cardiac Stress, and CMR Indices for the Entire Population (Obese and Obese/T2D Pooled)
| Variable | Inflammation | Dysglycemia and Insulin Resistance | Adiposity | Cardiac Stress and Fibrosis | |||||
|---|---|---|---|---|---|---|---|---|---|
| hsCRP | Serum Triglycerides | HOMA‐IR | Fasting Glucose | Hemoglobin A1c | Adiponectin | Leptin | NT‐Pro‐BNP | Gal‐3 | |
| LVEF | 0.18 | 0.28 | 0.15 | −0.03 | 0.22 | −0.39 | −0.08 | −0.11 | 0.08 |
| LVESV index | −0.17 | −0.08 | 0.15 | −0.29 | −0.47* | 0.19 | 0.19 | −0.09 | −0.04 |
| LVEDV index | −0.14 | −0.07 | 0.18 | −0.36 | −0.45* | 0.09 | 0.25 | −0.15 | −0.12 |
| LV mass index | −0.42 | −0.24 | 0.05 | −0.23 | −0.34 | −0.11 | −0.17 | −0.11 | −0.42 |
| LV mass/volume | −0.09 | −0.13 | −0.04 | 0.20 | 0.12 | −0.17 | −0.25 | 0.01 | −0.26 |
| LA volume index | 0.01 | 0.15 | 0.36 | 0.01 | −0.03 | −0.05 | 0.29 | −0.13 | −0.25 |
| Aortic PWV | −0.11 | 0.26 | −0.10 | 0.03 | 0.21 | −0.39 | −0.09 | −0.14 | 0.16 |
| Myocardial ECV | 0.47* | 0.51* | 0.29 | 0.29 | 0.76*** | −0.24 | −0.16 | 0.09 | 0.36 |
Each cell contains the Spearman correlation coefficient between the given CMR index (row) and the biomarker (column). LVESV, LVEDV, LV mass, and LA volume are all indexed to height. CMR indicates cardiac magnetic resonance imaging; T2D, type 2 diabetes; hsCRP, high‐sensitivity C‐reactive protein; HOMA‐IR, homeostatic model assessment of insulin resistance; NT‐pro‐BNP, N‐terminal probrain natriuretic peptide; Gal‐3, galectin‐3; LVEF, left ventricular ejection fraction; LVESV, left ventricular end‐systolic volume; LVEDV, left ventricular end‐diastolic volume; LA, left atrial; PWV, pulse wave velocity; ECV, extracellular volume fraction.
P<0.05,
**P<0.01,
P<0.005.